Using non-radioactive assay as a screening tool for membrane protein modulators is well-documented in scientific literature and has been widely used for studying the potassium channel family. The same principle of the nonradioactive Rb+ assay can be easily applied to more membrane protein targets than currently validated. The following publications represent a partial collection of ICR applications useful to both pharmaceutical labs and academic institutions. Please contact Aurora for further information regarding your specific protocol requirements.
Flux Assay Overview
Nonradioactive Rubidium Efflux Assay Technology for Screening of Ion Channels
Georg C. Terstappen