Aurora Biomed invited you to attend the 5th Annual Ion Channel Retreat. Our goal is to create a forum for scientific discourse spanning the spectrum of ion channel disciplines. Researchers from both academia and industry are invited to share knowledge for the advancement of ion channel research, drug discovery and safety pharmacology.
| June 25 Monday |
| Ion Channels as Disease Targets |
| 7:45 |
Registration and Breakfast |
| 8:50 |
Welcome |
| 8:55 |
Chairperson’s Remarks |
| 9:00 |
Sodium channel gating in health and disease
Bill Catterall
Professor and Chair, Dept. of Pharmacology
University of Washington |
| 9:30 |
Potassium channels of the pancreatic beta-cell: targets for the treatment of diabetes
James Herrington
Dept of Ion Channels
Merck |
| 10:00 |
Ion channels as targets for anti-viral drugs
Ling Chen
Director General
Guangzhou Institute of Biomedicine and Health |
| 10:30 |
Coffee Break |
| 10:50 |
Retigabine and therapeutic indications of targeting KCNQ family of voltage-gated K+ ion channels
Jim Wu
Scientific Advisor
Global Business Development
Valeant Pharmaceuticals |
| 11:20 |
Neuronal nicotinc acetylcholine receptors and human diseases
Daniel Bertrand
Professor
Dept of Neuroscience
University of Geneva |
| 11:50 |
Lunch |
| 1:15 |
Identification of á7 nAChR agonists with procognitive and neuroprotective properties for
treatment of AD
Georg Terstappen
Director of Research
Siena Biotech |
| 1:45 |
Large-scale mutation screen of human ion channel genes in episodic neurological disorders
Ron Lefreniere
General Manager & Director
Emerillon Therapeutics |
| 2:15 |
TRAM-34, a potential new drug for transplant rejection and stroke
Heike Wulff
Assistant Professor
Dept of Medical Pharmacology & Toxicology
University of California, Davis |
| |
|
| New Horizons in Life Sciences |
| 2:45 |
Chairman's Remarks |
| 2:50 |
Problems with directing the differentiation of stem cells and high-throughout solutions
Yen Choo
Chief Executive
Plasticell |
| 3:20 |
Chromosomal targeting in human embrionic stem cells
Uma Lakshmipathy
Senior Scientist
Stem Cells and Regenerative Medicine
Invitrogen |
| 3:50 |
TBA
Karimah Es Sabar
President
Life Sciences British Columbia |
| |
| June 26 Tuesday |
| Ion Channel Screening Technologies |
| 7:45 |
Breakfast |
| 8:30 |
Chairpersons remarks |
| 8:35 |
Ion channel drug discovery: From technology to strategy
Christian Wolff
Group Leader, Cell Biology
UCB Pharma |
| 9:05 |
Microelectrode-based biosensors and their applications in drug screening and safety
pharmacology
Elke Guenther
Head, Dept of Electrophysiology
University of Tubingen |
| 9:35 |
Development of calcium channel screening assays on QPatch-16
Michael Finley
Senior Scientist, Analgesics Team
Johnson & Johnson Pharmaceutical Research & Development |
| 10:05 |
Automated electrophysiology: A new era of ion channel drug discovery
Andy Swensen
Dept of Ion Channels
Merck |
| 10:35 |
P2x7 receptor antagonist screening using patch clamp
Michelle Dourado
Group Leader, Electrophysiology
Renovis |
| 11:05 |
Coffee Break |
| 11:20 |
Development of cell lines and assays for Ca2+ and ligand-gated ion channels
Umesh Patel
Director, Drug Discovery
Millipore Biosciences |
| 11:50 |
Electrophysiological techniques for functional ion channel screening with increased throughput
Horst Lohmann
Diaclean GmbH |
| 12:20 |
Application of flash luminescence in HTS for calcium channels
Alberto Di Silvio
Researcher, Screening Technologies
Axxam |
| 12:50 |
TBA
Sikander Gill
Director of Assay Development
Aurora Biomed |
| 1:20 |
Stepping up the discovery of potassium channel modulators with automated electrophysiology
Claire Townsend
Manager, Cellular Targets / Electrophysiology
GlaxoSmithKline |
| 1:50 |
High throughput identification, confirmation and selectivity testing of sodium channel inhibitors
using the IonWorksQuattro
Shannon Zellmer
Scientist III, HTEP/HTS |
| 4:30 |
Boat Cruise |
| |
| June 27 Wednesday |
| Ion Channels in Safety Pharmacology |
| 8:00 |
Breakfast |
| 8:45 |
Chairperson's Remarks |
| 8:50 |
An ion channel catalog for safety, selectivity and discovery screening
Arthur Brown
Chairman and CEO, Chantest
Professor, Dept of Physiology and Biophysics
Case Western Reserve University |
| 9:20 |
Nonclincal evaluation method for LQT prediction
Weimin Tang
Principal Scientist, ADMET
Johnson & Johnson Pharmaceutical Research & Development |
| 9:50 |
Cardiac safety assay tools
Stephen Hess
Research Fellow
Invitrogen Discovery Sciences |
| 10:20 |
Coffee Break |
| 10:40 |
TBA
Craig January
Professor of Medicine and Physiology
University of Wisconsin |
| Structure/Function of Ion Channel |
| 11:10 |
Chairperson’s Remarks |
| 11:15 |
MrgD activation inhibits KCNQ/M-currents and contributes to enhanced neuronal excitability
Robert Crozier
Discovery Neuroscience
Wyeth Research |
| 11:45 |
Endocytic trafficking of hERG potassium channels
Asipu Sivaprasadarao
Institute of Membrane and Systems Biology
Leeds University |
| 12:15 |
Lunch |
| 1:30 |
SK channels: Structure, function, and physiological roles
John Adelman
Senior Scientist, Vollum Institute
Oregon Health and Science University |
| 2:00 |
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and
modulates virus release
Bing Sun
Co-Director
Institut Pasteur of Shanghai |
| 2:30 |
Conformational changes in potassium channel-ligand complexes revealed by solid-state NMR
Olaf Pongs
Professor, Center for Molecular Neuroscience
University of Hamburg |
| 3:00 |
Closing Remarks |
