---
title: "Automation of On-Slide PCR Setup using VERSA™ 110 PCR"
description: "![VERSA 110 PCR Setup Workstation with module for Advalytix Amplislide ](https://www.aurorabiomed.com/wp-content/uploads/2014/02/Advalytix-Amplislide-300x167.png) VERSA 110 PCR Setup Workstation with module for Advalytix Amplislide The polymerase chain reaction (PCR) is a highly sensitive technique, enabling researchers to rapidly select and amplify a specific…"
url: "https://www.aurorabiomed.com/resources/on-slide-pcr-reaction-setup/"
updated: "2023-08-04"
category: Liquid Handling / Application Notes / Genomics
---

# Automation of On-Slide PCR Setup using VERSA™ 110 PCR

![VERSA 110 PCR Setup Workstation with module for Advalytix Amplislide ](https://www.aurorabiomed.com/wp-content/uploads/2014/02/Advalytix-Amplislide-300x167.png)
VERSA 110 PCR Setup Workstation with module for Advalytix Amplislide

The polymerase chain reaction (PCR) is a highly sensitive technique, enabling researchers to rapidly select and amplify a specific target sequence from a background of non-related sequences. It has been demonstrated that it is possible to perform PCR on samples adhered to microscope slides. In situ on slide PCR enables effective detection of low-copy sequences and permits cell-by-cell gene expression testing.

Advalytix’s AmpliSpeed slide thermocycler was specifically designed as a compact thermocycler capable of performing all PCR reactions on a standard glass slide. AmpliGrid glass slides have a special chemically structured surface with DNA free reaction centers. 5 µL of sealing solution must be applied to each droplet on the slide surface. This platform enables users desiring ultra low volume tests in the 1 µL range. This novel system maintains superior convenience, speed, sensitivity, efficiency and reproducibility. It is possible to analyze according to a cell by cell and/or gene by gene approach. Any template material that may be fixed to slides - including clinical or forensic stains and purified nucleic acids can be used with this approach.

 [DOWNLOAD APPLICATION NOTE](https://aurorabiomed.com/wp-content/uploads/2014/02/VERSA-Application-AmpliSlide.pdf)

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