Automated Solid Phase Extraction (SPE) System

VERSA automated Solid Phase Extraction systems (also known as automated SPE systems) fully automate SPE workflows from cartridge conditioning to sample derivatization. With the combination of the ReagentDrop™ dispenser, Heater-Shaker, Gripper, and Nitrogen Dryer, VERSA automated solid phase extraction (SPE) systems act to produce contamination-free sample pre-processing and trace analyte enrichment before performing sample analysis by a chromatography-based platform (HPLC, GCMS, HPLC-MS, etc).

The VERSA line of automated SPE systems are highly scalable for different throughputs and budgets. From the compact VERSA 10 to the highly customizable VERSA 1100, they can boost productivity in applications ranging from forensics, environmental samples, pharmaceutical compound analysis (ADME), metabolomics, and food safety.

Independently Validated

Dr. Thiangthum and Dr. Tanunkat from Bureau of Drug and Narcotic of Thailand use the VERSA 1100 automated Solid Phase Extraction system to quantify amphetamine and methamphetamine in drug users. They test more than 100,000 urine samples with VERSA automated SPE workstation each year.

Download the validation poster to see how the VERSA 1100 automated Solid Phase Extraction system is eliminating cross-contamination while ensuring accuracy and reproducibility in urine samples of drug users.

VERSA automated solia phase extraction system validation for toxicology

Modules Tailored for your Entire Automated SPE Workflow

Aurora Automation Compatible Solid Phase Extraction (SPE) Cartridges

Compatibility with Different Commercial Cartridges

1, 3, 6 mL Cartridges & 96 SPE Cartridge Plates

Current Gripper


moves cartridge block and nitrogen dryer for on-deck washing, elution, drying, and derivatization


allows efficient sample pre-processing and derivatization, streamlines complete automated SPE workflow

Vacuum Manifold for Negative Pressure SPE Automation

Vacuum Manifold (Negative Pressure)

ensures samples and reagents flow through cartridges efficiently

Nitrogen Dryer for Automated Solid Phase Extraction System (SPE Automation)

Nitrogen Dryer

enables on-deck sample drying/concentration prior to reconstitution/derivatization

Reagent Block Cooler

cools reagents for derivatization

Positive Pressure Module for VERSA Automated Solid Phase Extraction System

Positive Pressure Module

ensures samples and reagents flow through cartridges efficiently



dispenses reagents from off-deck reservoirs and eliminates tip usage – prevents dripping of volatile solvents

Cartridge Holder for SPE automation

SPE Cartridge Holder

works with the Gripper to automate conditioning, loading, washing, eluting, and fraction collecting steps

Automated Solid Phase Extraction flowchart
  • Capable of performing Automated Liquid Liquid Extraction on the same workstation
  • Compatibility with organic and aqueous reagents
  • Exhaust system available to remove volatile organic fumes
  • HEPA/UV/LED Enclosure – keeps samples contamination-free
  • Unparalleled Customer Service – our engineering team is readily available to troubleshoot your protocols


VERSA 1100 Automated Solid Phase Extraction (SPE) System

Deck Capacity 15
Pipetting Head

(Single Channel Function, Disposable Tip)

4 or 8 channel
ReagentDrop up to 8
Supported Cartridges 1, 3 or 6 mL cartridges or 96 SPE cartridge plate
Gripper Gripper
Pressure Module(s) 4 channel positive pressure module and/or vacuum manifold (negative pressure)
Nitrogen Dryer 24 or 96 channels
Shaker-Heater (2400rpm, RT to 90°C) Optional
Reagent Block Cooler Optional
Liquid Level Sensing Optional for Liquid Liquid Extraction
HEPA/UV/LED Enclosure Included
Width x Depth x Height (cm) 99 x 75 x 90
Weight (kg) 162

Applications – VERSA Automated Solid Phase Extraction Systems

  • Food Safety
  • Vitamin D from Blood/Serum Samples
  • Drugs of Abuse in Forensic Analysis
  • Compounds for Drug Discovery
  • Iso-Flavonoides from Urine Samples
  • Aflatoxins from Seafood Products
  • Growth Promoters in Blood
  • Semi-Volatile or Non-Volatile Analytes
  • Protein Precipitation

Frequently Asked Questions

VERSA is compatible with 1 mL, 3 mL, and 6 mL cartridges, in addition to 96-well SPE cartridge plates.

VERSA Automated Solid Phase Extraction (SPE) workstations fully automate SPE workflow from sample preparation and cartridge conditioning to sample derivatization on a single deck through the use of innovative, flexible modules. The combination of a Shaker-Heater, Nitrogen Dryer, and Gripper enables a complete walk-away solution for any SPE protocol including reconstitution of dried samples.

VERSA is equipped with either a 4 or 8 channel disposable tip syringe pipettor with single channel functionality, providing increased versatility and preventing cross-contamination.

Yes, the VERSA automated SPE workstation is capable of performing automated Liquid-Liquid Extraction on the same workstation. VERSA is highly scalable for different applications, throughputs, and budgets.

Yes, the VERSA Automated Solid Phase Extraction (SPE) workstation is equipped with a nitrogen dryer block that can be used for solvent evaporation and sample concentration after collection. Reconstitution in the organic or aqueous solvent of your choice can be easily conducted with the use of the ReagentDrop.

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