Automated Solid Phase Extraction (SPE) System

VERSA automated Solid Phase Extraction systems (also known as SPE systems) fully automate SPE workflow from cartridge conditioning to sample derivatization on a single deck with innovative modules. The same platform can also perform protein precipitation and liquid-liquid extraction (LLE), with options to have both Positive Pressure and Vacuum Manifold systems attached for various protocol functions. With the combination of the ReagentDrop™, Heater-Shaker, Gripper, and Nitrogen Dryer, these modules act to produce contamination-free sample pre-processing, and trace analyte enrichment, before performing sample analysis by a chromatography-based platform (HPLC / GC).

VERSA SPE systems and equipment are highly scalable for different throughputs and budgets. From the compact VERSA 10 to the highly customizable VERSA 1100, they assist applications in forensics, environmental samples, pharmaceutical compound analysis (ADME), clinical samples, and food safety.

Independently Validated

Dr. Thiangthum and Dr. Tanunkat from Bureau of Drug and Narcotic of Thailand use the VERSA 1100 automated Solid Phase Extraction system to quantify amphetamine and methamphetamine in drug users. They test more than 100,000 urine samples each year.

Download the validation poster to see how the VERSA 1100 automated Solid Phase Extraction system is eliminating cross-contamination while ensuring accuracy and reproducibility in urine samples of drug users.

SPE Equipment and Modules Tailored to Automate Your Entire Solid Phase Extraction Workflow

Compatibility with Different Commercial Cartridges

1, 3, 6 mL Cartridges & 96 SPE Cartridge Plates


moves cartridge block and nitrogen dryer for on-deck washing, elution, nitrogen drying and derivatization


allows efficient sample pre-processing and derivatization

Vacuum Manifold

Vacuum Manifold (Negative Pressure)

ensures samples and reagents flow through cartridges efficiently


Nitrogen Dryer

enables on-deck nitrogen drying for derivatization

Reagent Block Cooler

cools reagents for derivatization

SPE Positive Pressure Port

Positive Pressure Module

ensures samples and reagents flow through cartridges efficiently


draws reagents from their reservoirs and eliminates tip usage – prevents dripping of volatile solvents

SPE cartridge holder

SPE Cartridge Holder

works with Gripper to automate Wash, Elution and Fraction Collection steps

Solid Phase Extraction flowchart
  • Capable of performing Automated Liquid Liquid Extraction on the same workstation
  • Compatibility with organic and aqueous reagents
  • Exhaust system for volatile reagents available
  • HEPA/UV/LED Enclosure – keeps samples contamination-free
  • Unparalleled Customer Service – our engineering team is readily available to troubleshoot your protocols


VERSA 1100

Deck Capacity 15
Pipetting Head

(Single Channel Function, Disposable Tip)

4 or 8 channel
ReagentDrop up to 8
Supported Cartridges 1, 3 or 6 mL cartridges or 96 SPE cartridge plate
Gripper Gripper
Pressure Module(s) 4 channel positive pressure module and/or vacuum manifold (negative pressure)
Nitrogen Dryer 24 or 96 channels
Shaker-Heater (2400rpm, RT to 90°C) Optional
Reagent Block Cooler Optional
Liquid Level Sensing Optional for Liquid Liquid Extraction
HEPA/UV/LED Enclosure Included
Width x Depth x Height (cm) 99 x 75 x 90
Weight (kg) 162


  • Food Safety
  • Vitamin D from Blood/Serum Samples
  • Drugs of Abuse in Forensic Analysis
  • Compounds for Drug Discovery
  • Iso-Flavonoides from Urine Samples
  • Aflatoxins from Seafood Products
  • Growth Promoters in Blood
  • Semi-Volatile or Non-Volatile Analytes
  • Protein Precipitation

Frequently Asked Questions

VERSA is compatible with 1 mL, 3 mL and 6 mL cartridges as well as 96-well SPE cartridge plates.

VERSA Automated Solid Phase Extraction (SPE) workstations fully automate SPE workflow from sample preparation and cartridge conditioning to sample derivatization on a single deck through the use of innovative, flexible modules. The combination of a Shaker-Heater, Nitrogen Dryer and Gripper enables complete walk-away solution for any SPE protocols including reconstitution of dried samples.

VERSA is equipped with a 4 or 8 channel disposable tip syringe pipettor with single channel functionality which offers versatility and prevents cross-contamination.

Yes, the VERSA SPE workstation is capable of performing automated Liquid-Liquid Extraction on the same workstation. VERSA is highly scalable for different applications, throughputs and budgets.

Yes, VERSA Automated Solid Phase Extraction (SPE) workstation is equipped with a nitrogen dryer block that can be used for solvent evaporation and sample concentration after collection.

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