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Next Generation Sequencing / Massively Parallel Sequencing Library & Sample Preparation

Flexible & Cost-Effective Solution for Automated NGS/MPS Library & Sample Preparation

VERSA’s innovative modules are designed to tackle challenging steps of the Automated Next Generation Sequencing (NGS)/ Massively Parallel Sequencing (MPS) library and sample preparation protocols. The Magnetic Bead Vortex ensures homogeneous bead suspension and distribution. The combination of ReagentDrop bulk reagent dispensing module and 96-Tip Aspirator offers fast and efficient bead washing steps while saving tip costs. The VERSA Automated Next Generation Sequencing/Massively Parallel Sequencing library and sample preparation workstations are compatible with various commercial kits, reagents and labware. VERSA automated NGS/MPS library and Sample preparation workstations are highly scalable for different throughputs and budget.

Independently Validated

Dr. Catherine Dumur from Virginia Commonwealth University is using VERSA NGS/MPS Library & Sample Preparation workstation to automate Ion AmpliSeq CHP2 assay.

Download the checkerboard validation to see how the VERSA Automated NGS/MPS Library & Sample Preparation workstation is eliminating cross-contamination while demonstrating incomparable reproducibility on all patient DNA samples.

Validation from Ion AmpliSeq Cancer Hotspot Panel

Modules Tailored to Automated NGS/MPS Library & Sample Preparation Protocols

Magnetic Bead Vortex

ensures homogeneous bead suspension

96 Tip Aspirator

increases efficiency and speed while reducing tip costs

Shaker-Heater

Shaker-Heater

allows efficient sample processing

Shaker-Heater-Magnet-Elevator

Shaker-Heater-Magnet Elevator

reduces protocol time

ReagentDrop

draws reagents from their reservoir and eliminates tip usage

Gripper

moves sample plates between Magnetic Bead Seperator and Shaker for on-deck mixing and washing

Reagent Block Cooler

preserves precious dNTPs, buffers and enzymes

magnetic-bead-separator

Magnetic Bead Separator

pulls down magnetic beads for sample purification

  • Open System – compatible with diverse reagents, kits and labware
  • HEPA/UV/LED Enclosure – keeps samples contamination-free
  • Scalable Solution – processes 1 to 96 samples in parallel depending on throughput demands
  • Unparalleled Customer Service – our engineering team is readily available to troubleshoot your protocols

 

Specifications

VERSA 10 Gene Liquid Handling SolutionVERSA 10 Gene VERSA 1100 Gene Liquid Handling SolutionVERSA 1100 Gene
Deck Capacity 6 15
Pipetting Head

(Single Channel Function, Disposable Tip)

8 channel 8 or 96 channel
ReagentDrop N/A 8
96-Tip Aspirator N/A 1
Temperature Regulation Block 1 4
Reagent Cooling Block 1 1
Plate Shaker 1 1*
Magnetic Block 1 1*
Gripper / Plate Transporter Plate Transporter Gripper
Liquid Level Sensing Optional Optional
HEPA/UV/LED Enclosure Optional Included
Width x Depth x Height (cm) 65 x 43 x 52 98.5 x 75.2 x 108.2
Weight (kg) 27 200

*Could be upgraded to Shaker-Heater-Magnet Elevator

Applications

  • DNA/RNA Purification and Cleanup
  • DNA/RNA Fragment Size Selection
  • Enzymatic Reaction Setup
  • Library Normalization and Pooling
  • Single and Multiplex RT-PCR Setup
  • Sequencing Reaction Setup
  • Oligo-based Gene Synthesis Setup
  • Magnetic Bead Based Applications

Frequently Asked Questions

Our VERSA automated workstations are very flexible and open systems and are compatible with almost all the Next Generation Sequencing (NGS) library and sample preparation kits, reagents and labware in the market.

Yes, the VERSA Automated Nucleic Acid Extraction and Purification workstation is equipped with a Heater-Cooler Plate and Heater-Shaker that can be used for incubating samples at temperatures from 2 – 92°C.

All the steps from DNA/RNA purification and cleanup, DNA/RNA fragment size selection, enzymatic reaction setup, library construction, normalization and pooling, single and multiplex real-time PCR setup, sequencing reaction setup can be automated on VERSA. Transferring the plate to thermocycler for PCR reaction and centrifuging steps should be done manually.

Yes, when manual intervention is required, a pause message can be defined to pop up on the monitor to notify the user about the next manual steps. VERSA Automated NGS library and sample prep system can also email the pause notifications to users who should take responsibility for the step.

No, the ReagentDrop dispensing speed on VERSA automated NGS library and sample preparation workstation is always optimized for reagents with different consistency to avoid splashing.

No, we have validated VERSA for automating different applications and have not observed any cross-contamination issues. VERSA automated NGS library prep workstation utilizes disposable tips to eliminate cross-contamination, additionally the aspirating and dispensing speed is carefully adjusted to avoid splashing or carry-over contamination. VERSA is also equipped with HEPA filter and UV light to keep the environment contamination-free.

VERSA is a very flexible and open system and is capable of preparing libraries / samples for any NGS instrument.

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