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High Throughput Screening Flux Assays

Aurora employs proprietary flux assays technology in which non-radioactive ions are used as tracers for specific ion channels and transporters. Tracer ions are loaded into either cells or extracellular solutions. High-throughput screening is offered on Aurora’s high throughput flux assay-based ICR 8000 and ICR12000 systems. Results obtained by our cell based functional assays screen are comparable to results generated by the gold standard patch clamp. When combined with Aurora’s ICR technology, these channels assay are an advantageous primary screening method for drug discovery.

icr-8000

icr-12000

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