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Automated Solid Phase Extraction (SPE) System

VERSA-1100, Automated liquid handling System, with 15-positioned modular deck configuration with options such as magnetic bead vortex, shaker-heater and ReagentDrop, For 96 well plates and 384 well plates.Aurora’s automated mass spectrometry sample preparation workstations for both Solid Phase Extraction (SPE) and Liquid-Liquid Extraction (LLE).

Automated Solid Phase Extraction (SPE) System


VERSA automated Solid Phase Extraction systems (also known as automated SPE systems) fully automate SPE workflows from cartridge conditioning to sample derivatization. With the combination of the ReagentDrop™ dispenser, Heater-Shaker, Gripper, and Nitrogen Dryer, VERSA automated solid phase extraction (SPE) systems act to produce contamination-free sample pre-processing and trace analyte enrichment before performing sample analysis by a chromatography-based platform (HPLC, GCMS, HPLC-MS, etc).

The VERSA line of automated SPE systems are highly scalable for different throughputs and budgets. From the compact VERSA 10 to the highly customizable VERSA 1100, they can boost productivity in applications ranging from forensics, environmental samples, pharmaceutical compound analysis (ADME), metabolomics, and food safety.

Independently Validated

Dr. Thiangthum and Dr. Tanunkat from Bureau of Drug and Narcotic of Thailand use the VERSA 1100 automated Solid Phase Extraction system to quantify amphetamine and methamphetamine in drug users. They test more than 100,000 urine samples each year.

Download the validation poster to see how the VERSA 1100 automated Solid Phase Extraction system is eliminating cross-contamination while ensuring accuracy and reproducibility in urine samples of drug users.

Modules Tailored for your Entire Automated SPE Workflow

Compatibility with Different Commercial Cartridges

1, 3, 6 mL Cartridges & 96 SPE Cartridge Plates

Current Gripper


moves cartridge block and nitrogen dryer for on-deck washing, elution, drying, and derivatization


allows efficient sample pre-processing and derivatization, streamlines complete automated SPE workflow

Vacuum Manifold (Negative Pressure)

ensures samples and reagents flow through cartridges efficiently

Nitrogen Dryer

enables on-deck sample drying/concentration prior to reconstitution/derivatization

Reagent Block Cooler

cools reagents for derivatization

Positive Pressure Module

ensures samples and reagents flow through cartridges efficiently



dispenses reagents from off-deck reservoirs and eliminates tip usage – prevents dripping of volatile solvents

SPE Cartridge Holder

works with the Gripper to automate conditioning, loading, washing, eluting, and fraction collecting steps

  • Capable of performing Automated Liquid Liquid Extraction on the same workstation
  • Compatibility with organic and aqueous reagents
  • Exhaust system available to remove volatile organic fumes
  • HEPA/UV/LED Enclosure – keeps samples contamination-free
  • Unparalleled Customer Service – our engineering team is readily available to troubleshoot your protocols


VERSA 1100 Automated Solid Phase Extraction (SPE) System

Deck Capacity15
Pipetting Head

(Single Channel Function, Disposable Tip)

4 or 8 channel
ReagentDropup to 8
Supported Cartridges1, 3 or 6 mL cartridges or 96 SPE cartridge plate
Pressure Module(s)4 channel positive pressure module and/or vacuum manifold (negative pressure)
Nitrogen Dryer24 or 96 channels
Shaker-Heater (2400rpm, RT to 90°C)Optional
Reagent Block CoolerOptional
Liquid Level SensingOptional for Liquid Liquid Extraction
HEPA/UV/LED EnclosureIncluded
Width x Depth x Height (cm)99 x 75 x 90
Weight (kg)162

Applications – VERSA Automated Solid Phase Extraction Systems

  • Food Safety
  • Vitamin D from Blood/Serum Samples
  • Drugs of Abuse in Forensic Analysis
  • Compounds for Drug Discovery
  • Iso-Flavonoides from Urine Samples
  • Aflatoxins from Seafood Products
  • Growth Promoters in Blood
  • Semi-Volatile or Non-Volatile Analytes
  • Protein Precipitation

Streamline Your COVID-19 Diagnostic Workflow

Aurora’s VERSA automated RNA extraction machine offers a fully automated solution to streamline magnetic beads based viral RNA extraction and PCR reaction setup. VERSA 10 and VERSA 1100 are compatible with most of the commercially available reagent kits as well as in-house developed chemistries. Trusted by many healthcare professionals, VERSA RNA extraction machine has been playing an important role in helping to expand testing capacity during the COVID-19 pandemic. Please contact us to learn more about Aurora’s automated detection solution for COVID-19.

Get more information on the VERSA Automated Extraction Workstations!

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