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Aurora’s Ion Channel Reader helps TRPV1 research

On October 4, 2021, the Nobel Prize in Physiology and Medicine was awarded to David Julius and Ardem Patapoutian. David Julius discovered the temperature receptor, TRPV1 ion channel, and Ardem Patapoutian discovered the pressure receptor, PIEZO ion channel.

Their discoveries explain how we perceive temperature and touch, leading to a “revolution” in neuroscience and providing new insights into human physiology and disease.

Capsaicin from Chili by David Julius. Diagram shows the Capsaicin molecule from red chili. The molecule triggers a ion channel called TRPV1 which makes us feel heat.

David Julius used capsaicin from chili peppers to identify TRPV1, an ion channel activated by painful heat. Credit: The Nobel Assembly at Karolinska Institutet

AstraZeneca: User of Aurora’s Ion Channel Reader for TRPV1 research

Ion Channel Reader, ICR 8000 by Aurora Biomed Inc. How Aurora's Ion Channel Reader helps with the TRPV1 research. ICR8000 tray with logo.

 Aurora’s Ion Channel Reader

Novel methodology to identify TRPV1 antagonists independent of Capsaicin activation. Journal of Biomolecular screening. Stephen Zicha, Olivier Radresa, Patricia Laplante, Michael Morton, Karen Jones, Martin Main, Shepali Trivedi, Ron p. Julien, Andrew Griffin, Jean Labrecque, Sultan Ahmad, and William Brown