Automated Next Generation Sequencing / Massively Parallel Sequencing Library & Sample Preparation

VERSA’s innovative modules are designed to tackle the challenging steps of automating Next Generation Sequencing (NGS) library preparation and sample preparation protocols (also known as Massively Parallel Sequencing or MPS). The Magnetic Bead Vortex ensures homogeneous bead suspension and distribution. The combination of ReagentDrop bulk reagent dispensing module and 96-Tip Aspirator offers fast and efficient bead washing steps while saving tip costs. The VERSA automated Next Generation Sequencing library preparation and sample preparation workstations are compatible with various commercial kits, reagents, and labware. VERSA automated NGS/MPS library and sample preparation workstations are highly scalable for different throughputs and budget.

Independently Validated

Validation of an Automated Method for Library Preparation for a Next-Generation Sequencing-Based Assay for Oncology.

Download the checkerboard validation to see how the VERSA automated NGS library and sample preparation workstation is eliminating cross-contamination while demonstrating incomparable reproducibility on all patient DNA samples.


VERSA Automated Nucleic Acid Extraction and Purification

VERSA 1100

Deck Capacity 15
Pipetting Head

(Single Channel Function, Disposable Tip)

8 or 96 channel or 4 channel with independent Z-axis
ReagentDrop 8 channels
Magnetic Block 1
Temperature Regulation Block 2
Reagent Cooling Block 1
Plate Shaker 1
Gripper 1
96-Tip Aspirator Optional
Liquid Level Sensing Optional
HEPA/UV/LED Enclosure Included
Width x Depth x Height (cm) 98.5 x 75.2 x 108.2
Weight (kg) 200


Modules Tailored to Automated NGS/MPS Library and Sample Preparation Protocols

Magnetic Bead Vortex

ensures homogeneous bead suspension

96 Tip Aspirator

increases efficiency and speed while reducing tip costs

Heater Shaker with PCR plate


allows efficient sample processing


Reagent Block Cooler

preserves precious dNTPs, buffers and enzymes


draws reagents from their reservoir and eliminates tip usage


moves sample plates between Magnetic Bead Separator and Shaker for on-deck mixing and washing

New Round Bottom Magnet Plate

Magnetic Bead Separator

pulls down magnetic beads for sample purification

  • Open System – compatible with commercially available kits including Illumina, Thermo Fisher, etc…
  • HEPA/UV/LED Enclosure – keeps samples contamination-free
  • Scalable Solution – processes 1 to 96 samples in parallel depending on throughput demands
  • Unparalleled Customer Service – our engineering team is readily available to troubleshoot your protocols


Magnetic Bead Vortex – The Aurora Advantage

Aurora’s unique magnetic bead vortexer specifically addresses the painful process of ensuring the bead mixture is sufficiently homogenized as critically outlined in all protocols when prepping libraries.

Immediately prior to use, vortex the beads until they are well dispersed. The color of the liquid should appear homogeneous.

Take care to minimize bead loss which can impact final yields. 

It is critical to resuspend the beads at the bottom of the tube… Resuspension is essential for achieving consistent cluster density to optimize the resolution of individual libraries when pooled together

Vortex beads before each use. Vortex beads frequently to make sure that beads are evenly distributed

– Illumina™ NGS Sample Preparation Protocol


  • DNA/RNA Purification and Cleanup
  • DNA/RNA Fragment Size Selection
  • Enzymatic Reaction Setup
  • Library Normalization and Pooling
  • Single and Multiplex RT-PCR Setup
  • Sequencing Reaction Setup
  • Oligo-based Gene Synthesis Setup
  • Magnetic Bead Based Applications

Frequently Asked Questions

Our VERSA automated workstations are very flexible and open systems and are compatible with almost all the Next Generation Sequencing (NGS) library and sample preparation kits, reagents and labware in the market.

Yes, the VERSA Automated Nucleic Acid Extraction and Purification workstation is equipped with a Heater-Cooler Plate and Heater-Shaker that can be used for incubating samples at temperatures from 2 – 92°C.

All the steps from DNA/RNA purification and cleanup, DNA/RNA fragment size selection, enzymatic reaction setup, library construction, normalization and pooling, single and multiplex real-time PCR setup, sequencing reaction setup can be automated on VERSA. Transferring the plate to thermocycler for PCR reaction and centrifuging steps should be done manually.

Yes, when manual intervention is required, a pause message can be defined to pop up on the monitor to notify the user about the next manual steps. VERSA Automated NGS library and sample prep system can also email the pause notifications to users who should take responsibility for the step.

No, the ReagentDrop dispensing speed on VERSA automated NGS library and sample preparation workstation is always optimized for reagents with different consistency to avoid splashing.

No, we have validated VERSA for automating different applications and have not observed any cross-contamination issues. VERSA automated NGS library prep workstation utilizes disposable tips to eliminate cross-contamination, additionally the aspirating and dispensing speed is carefully adjusted to avoid splashing or carry-over contamination. VERSA is also equipped with HEPA filter and UV light to keep the environment contamination-free.

VERSA is a very flexible and open system and is capable of preparing libraries / samples for any NGS instrument.

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