Automation of Sanger Sequencing

Automation of Sanger Sequencing

Sanger sequencing has been a standard tool for both academia and industry for over 30 years. It has been relied on for the sequencing of genomes, and is regularly employed by primary research labs, medical genetics facilities and other groups looking to sequence small numbers of amplicons or genetic loci. In the face of high throughput next generation sequencing technologies, Sanger sequencing protocols are still relevant due to the minimal overall procedural costs, and the relatively long sequence read length.

Aurora is a globally recognized solution provider of lab automation equipment for genomic science applications. As groups utilizing Sanger sequencing increase the scale of their workload, the need to introduce consistency and reliability to the DNA cleanup process becomes evident. By employing Solid Phase Reverse Immobilization (SPRI) technology, such cleanups can be reliably automated using magnetic bead platforms.

The VERSA Nucleic Acid Preparation workstation is a mature, small footprint instrument optimized for quickly preparing samples for loading onto capillary electrophoresis systems. Aurora offers the 8-channel VERSA Gene workstation for groups with higher throughput Sanger sequencing needs. Both systems are open platforms and work with kits provided by 3rd parties, allowing the user to continue working with the consumables they are familiar with.